is there sulfa in the covid vaccinecalifornia lutheran university nursing

Prior to licensure, as part of FDAs evaluation, FDA takes all of the ingredients of a vaccine into account, including the active ingredients as well as other substances. Sulfasalazine (Azulfidine), used to treat Crohn's disease, ulcerative colitis and rheumatoid arthritis Dapsone, used to treat leprosy, dermatitis and certain types of pneumonia Keep in mind that if you have a reaction to a sulfonamide antibiotic, you may still be able to take other sulfonamide medications without having a reaction. Allergists are using laxatives to find out if patients have sensitivity to the COVID-19 vaccines. There was previous anaphylaxis to: a rabies vaccine, sulfa drugs, a jellyfish sting, walnuts, an anti-nausea medication, a flu vaccine and one case was unspecified. 90% of the anaphylaxis patients were women, however 65% of those vaccinated were also women. The median age was 40 years old; there were no clusters of reactions by geography. Hypersensitivity reactions to non beta-lactam antimicrobial agents, a statement of the WAO special committee on drug allergy. Sulfonamides, Sulphur allergy symptoms: Foods to avoid with sulfa allergy. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. There is no egg or egg-related component of the RNA vaccines, says Baker. Yes. In Britain, the initial vaccine rollout started on Dec. 8, 2020. Bells Palsy fact-check:During the Pfizer trial, four cases of Bells palsy (temporary facial paralysis) emerged in the treatment group and there were four cases in the Moderna trial (three in the treatment group and one with a placebo patient). The Pfizer-BioNTech COVID-19 vaccine is administered into the muscle in two doses, three weeks apart (here ). And for more up-to-date information, sign up for our daily newsletter. If you're unfamiliar with them, antibodies are proteins your immune system makes to fight infections like viruses. Sometimes the shots can cause mild flu-like symptoms as a side effect. Cloned fetal cells (not fetal tissue) are sometimes used in the development, confirmation or production process of making vaccines including the COVID-19 vaccine ( here ,here ). A syringe with a vaccine is seen ahead of trials by volunteers testing for the coronavirus disease (COVID-19), and taking part in the country's human clinical trial for potential vaccines at the . While the vaccine is highly effective at preventing symptomatic and severe disease, it is not 100% effective, and it is not yet known how well it prevents asymptomatic infection, or how long its effects will last. Are the mRNA vaccines safe for people with egg allergy? The authors who reviewed the anaphylaxis reports also say that all facilities administering COVID-19 vaccines should have the necessary supplies and trained medical personnel available to manage anaphylaxis.. Vaccines contain proteins that resemble part of an infectious organism to create an immune response in your body, including antibodies. Numerous studies have shown that sulfur doping can change the electron distribution of nitrogen-doped carbon materials, which facilitates the catalytic process and provides stability [21,22,23]. Is polyethylene glycol (PEG) to blame for the few anaphylaxis cases to the vaccines? Post treatment:Your severe reaction should be reported through the CDCs Vaccine Adverse Events Reporting System (VAERS). TritionX-100 is a detergent used in spermicide. But scientists have never used mRNA technologythe method used to create the Pfizer-BioNTech vaccineto develop a vaccine, so it's understandable for people to have questions about its ingredients. The short answer is yes. A man receives the COVID-19 vaccine at a gymnasium on March 18, 2021 in Beijing, China. A sulfa allergy occurs when a person has an allergic reaction to drugs that contain chemicals called sulfonamides. Although the number of reported cases of anaphylaxis to the mRNA vaccines remains small relative to the shots administered,Dr. Alkis Togiaswith the National Institute of Allergy and Infectious Diseases (NIAID) told Allergic Living about a nationwide clinical trial involving people with a history of severe allergic reactions. The makers of thePfizer-BioNTech vaccinemade the vaccine ingredients available to the public. Both recovered at the time of the CDC report. They can also remain in your body, helping fend off future illnesses by those same infections. Coronavirus updates: Vaccine distribution has begun; FDA officials assure public that Pfizer vaccine is safe. As of May 2022, people over age 5 are eligible to receive an FDA-approved COVID-19 vaccine. 14304, Allergic Living Like any vaccine, the COVID-19 vaccines do come with potential side effects. In the Johnson & Johnson trials, the vaccine has been 100% effective in preventing hospitalizations and death from COVID-19 illness. Further to Food and Latex:The American College of Allergy, Asthma, and Immunology (ACAAI) notes that individuals with allergies to medications, foods, inhalants, insects, and latex are probably no more likely than the general public to have an allergic reaction to the mRNA COVID-19 vaccines.. While many people lose their sense of smell and taste after contracting COVID-19, there's a new side effect in some recovering patients random whiffs of a burning scent, and sulfur or fish. He . information and will only use or disclose that information as set forth in our notice of (2010, December 31). Aluminum is not an ingredient in the Pfizer-BioNTech and Moderna COVID-19 vaccines, as explained by an expert here . The CDC counsels caution when considering vaccination for:A person with a history of anaphylaxis to another vaccine or a history of anaphylaxis to an injectable medication thats not related to a component of mRNA vaccines or polysorbate. a long-term care home) or because of job-related risk. In large clinical trials, the mRNA vaccines proved highly effective in preventing the coronavirus. Since December of 2020, more than 390 million doses of COVID-19 vaccines have been given in the United States. Last medically reviewed on March 27, 2018, People add cinnamon to many foods and desserts for its tangy, exciting taste and its health benefits. If you have HIV/AIDS, you may have an increased sensitivity to sulfonamide medications. While not required, the agency also prefers that additional tools are available, including: a pulse oximeter, oxygen, albuterol and intravenous fluids. Those who have had allergic reactions to things such as food, latex, pollen and bee stings should still get the COVID-19 vaccine, Winokur said. The post reads: The CDCs new slogan is #VaccinateWithConfidence. Suite 6-168 American College of Allergy, Asthma & Immunology. An independent panel advising the FDA reviewed the data on the Moderna mRNA vaccine and voted strongly to recommend the FDA give an EUA to the vaccine, initially for those 18 and older. More data are needed to determine what protection these antibodies may provide to the baby., TheAmerican Academy of Pediatrics(AAP), American College of Obstetricians and Gynecologists (ACOG) and other agencies who are maternal care experts are urging pregnant women and lactating women to get the COVID-19 vaccine. And if you're eager to get your shot, These Are the First Pharmacies Where You Can Get the COVID Vaccine. These include injection site pain, fatigue, headache, muscle or joint pain, chills or vomiting. Quinolones, including Cipro and Levaquin. By clicking Accept All Cookies, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. When evaluating a vaccine for safety and efficacy, FDA considers adjuvants as a component of the vaccine; they are not licensed separately. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. The vaccine is not commercially available, but included within the U.S. governments National Stockpile if public health officials determine it is needed. On Dec. 24, 2020,a Boston doctorbecame the first to experience anaphylaxis to the Moderna vaccine. These antibiotics include combination drugs: Other types of sulfa medications may trigger a reaction in some people who have a sulfonamide antibiotic allergy: Keep in mind that if you have a reaction to a sulfonamide antibiotic, you may still be able to take other sulfonamide medications without having a reaction. This website uses cookies so that we can provide you with the best user experience possible. CDC Recommends COVID Vaccines for Kids Under 5Here's When Shots Could Go in Little Arms, COVID-19 Vaccines for Kids 12 to 15: Your Biggest Fears Addressed by Experts, Is the COVID-19 Vaccine Safe for Everyone? COVID-19 vaccine ingredients are considered safe for most people. other information we have about you. An official website of the United States government, : And thanks to the cooperation of scientists worldwide, we now have a life-saving vaccine in our pandemic toolbox. Some people can also experience more severe reactions, such as anaphylaxis and Steven-Johnson syndrome. The hospital emergency physician who treated her told a virtual press briefing (attended by AllergicLiving) that the woman had a red rash on her face and experienced shortness of breath and an elevated heart rate. There are no diagnostic tests for sulfa allergy. The Moderna COVID-19 vaccine (Spikevax) also uses mRNA technology. What severe reactions have occurred in the U.S.? MRC-5 cells are human male aborted fetus; WI-38 are female. Caffeine is present is some of the most popular drinks worldwide. In the United States the Pfizer and Moderna COVID-19 vaccines have Emergency Use Authorization from the U.S. Food and Drug Administration (FDA) but they are not yet fully FDA-approved. To date, no deaths or long-term consequences have been reported following allergic reactions to any of the COVID-19 vaccines. Mayo Clinic does not endorse any of the third party products and services advertised. For the flu shot seethis linkfor the MMR seethis link. The Pfizer-BioNTech COVID-19 Vaccine is a sterile, preservative-free, frozen suspension for muscle injection. A person with a sulfa allergy can experience severe complications. Nat Med. There is no latex in the mRNA COVID-19 vaccines. "Nobody died from COVID, who received the vaccine," Greenberg said. Preservatives are added to some vaccine formulations to prevent the growth of bacteria or fungi that may be introduced into the vaccine during its use, e.g., repeated puncture of a multi-dose vaccine vial with a needle. The risk of a severe case of coronavirus disease because of age or medical conditions. A person who has a sulfa allergy will not necessarily have a sulfite allergy, so there is no cross-reactivity. Both say there is no soy protein or other food protein in the mRNA vaccines. Social media users have been sharing posts online that claim COVID-19 vaccines contain human aborted fetus cells, triton X-100, thimerosal, and aluminum. Sulfonamide allergy in HIV-uninfected patients. And as of May 2022, they expanded the emergency use authorization to include children between five and 11 who received their primary vaccine five months prior. On Dec. 15, a nurse at a hospital in Juneau, Alaska, became the first reported American case of anaphylaxis to the Pfizer vaccine. Formaldehyde has a long history of safe use in the manufacture of certain viral and bacterial vaccines. Vaccine providers should observe patients with a history of anaphylaxis (due to any cause) for 30 minutes after vaccination, the agency says. Importantly, she adds as a drug allergy expert: Soy-allergic patients tolerate PEG all the time., In rare cases, PEG has triggered allergic reactions. Last year, experts warned that the 2021-2022 flu season would be bad, largely because they thought the flu would make a comeback as many people dropped COVID precautions. And for more on the current state of the pandemic, The New COVID Strain Is Now in These 8 States. If you're wondering what's in it we have a list of ingredients here. Also, sulfa is different from sulfates and sulfur. Doctors and pharmacists use drugs that contain sulfa to treat many conditions, including skin disorders, eye infections, and rheumatoid arthritis. Aluminum salts are incorporated into some vaccine formulations as an adjuvant. An allergy to sulfonamide medications is different from having an adverse reaction to wine or food that contains sulfites. ), A studyled by allergists at Massachusetts General Hospital notes that an FDA review between 2005 and 2017 showed an average of just four cases of PEG anaphylaxis per year. Thimerosal is 49.5% mercury. The information in this story is accurate as of press time. Mayo Clinic does not endorse companies or products. These precautions include monitoring these patients a little longer. They are used to reduce bacterial growth in eggs during processing steps, because eggs are not sterile products. Only minute quantities remain in vaccines (see table below). But this begs the question -- what is in the vaccine? Of note, the most common source of exposure to aluminum is from eating food or drinking water. She was given epinephrine. According to the Union health ministry, a total of 3 . Learn how to identify and manage allergies here. This article was produced by the Reuters Fact Check team. Montanaro, A. If you disable this cookie, we will not be able to save your preferences. If you are a Mayo Clinic patient, this could The amount of formaldehyde present in some vaccines is so small compared to the concentration that occurs naturally in the body that it does not pose a safety concern. Do You Need the Vaccine if You've Already Had COVID-19? Of the 21 patients who developed anaphylaxis (which includes the Alaska nurse but not the Boston doctor), 17 had history of allergies or allergic reactions to drugs or to foods or insect stings. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. In this article, we look at the signs and symptoms of a sulfa allergy, medications to avoid, complications, and treatment. 2100 Bloor Street West Formaldehyde is also produced naturally in the human body as a part of normal functions of the body to produce energy and build the basic materials needed for important life processes. These small quantities of antibiotics have never been clearly found to cause severe allergic reactions. The Centers for Disease Control and Prevention (CDC) says that any patient with a history of allergic reaction to any vaccine or injectable therapy and anyone with a history of severe allergic reaction, known as anaphylaxis, should be monitored for 30 minutes after their shot. Highly trained FDA scientists and clinicians carefully evaluate all of the information in a marketing application and make a determination whether to license (approve) a vaccine before it can be used in the United States. Some people, especially after the second vaccine, will get fevers, chills, and muscle aches. These are medical emergencies. What happens if you have an allergic reaction after receiving the vaccine. When the body breaks down formaldehyde, it does not distinguish between formaldehyde from vaccines and that which is naturally produced or environmental. The CDC looked into these patients' past history of allergies and allergic reactions, and shared their findings. The CDC advises those with a known allergy to PEG not to get the vaccine. U.S. Food and Drug Administration (FDA). But mRNA vaccines work differently and contain no live virus.The CDC explainsthat these vaccines instead teach our cells how to make a protein or even just a piece of a protein that triggers an immune response. This leads the immune system to produce antibodies against the virus, which will protect an inoculated person who gets exposed to the real virus. None were considered serious or required epinephrine. Investigationcontinues into the cause of the few serious reactions to the COVID-19 vaccines. Understandably, some people who have a sulfa allergy might think that they are allergic to sulfites, too, because the names of the two chemicals are similar. The timing of administering the boosters change based on our growing understanding of the virus and the duration of protection from COVID-19 infection. CDC strengthens recommendations and expands eligibility for COVID-19 booster shots. The study authored by Wolfson, Blumenthal and colleagues offers guidance to allergists and patients. Montanaro A. Sulfonamide allergy in HIV-uninfected patients. They may recommend an appointment with a specialist to carry out further tests and give advice on which medications and products to avoid. If you enroll someone whos had anaphylaxis to a prior vaccine and then they have anaphylaxis to this vaccine, it just clouds all the data. Stukus also stressed that true anaphylaxis to any vaccine is rare., Related Reading:J&J Vaccine: Allergists Assess Safety and Reaction RisksCOVID-19 Vaccines: How to Tell an Allergy from a Side Effect; Plus COVID armLikely More than 1 Cause of COVID-19 Vaccine ReactionsCDC Update: Severe Reactions to COVID-19 Vaccines Are Rare, Women Most Affected Some Reactions to Vaccines Expected; But Not Reason to Avoid ShotCDCs FAQ of General COVID-19 Vaccination Questions, E-Mail: pollen, dust) or latex allergies. A history of allergy to oral medications. Non-serious allergy to vaccines or other injectables (e.g. 2021;27(7):1205-1211. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Drug allergies. Data from tens of thousands of reporting individuals have shown that the COVID-19 vaccine is both safe and effective when administered during pregnancy. Excessive exposure to formaldehyde may cause cancer, but the latest research has shown that the highest risk is from the air when formaldehyde is inhaled from breathing, and occurs more frequently in people who routinely use formaldehyde in their jobs. The agency says such patients may want to consult an allergist for advice about potential risks and balance these against the benefits of vaccination. The CDC specifically says no gelatin or preservatives are used in either of the mRNA vaccines. At the. Everyone will need to continue taking precautions like masking and physical distancing until the spread has stopped. In a September 2021 consensus statement, they wrote: Maternal care experts want the best outcomes for their patients, and that means both a healthy parent and a healthy baby. In its guidance to doctors on the Pfizer and Moderna vaccines, the CDC says: 1. Australia's COVID-19 vaccines have undergone rigorous testing They both come in multi-dose vials, but only the Pfizer needs diluting Pharmaceutical ingredients are added to stabilise the vaccines Before sharing sensitive information, make sure you're on a federal government site. Several readers asked about dairy and gelatin in relation to either dairy allergy or alpha-gal allergy. It includes mRNA, lipids, cholesterol, 1,2-distearoyl-sn-glycero-3-phosphocholine, tromethamine, tromethamine hydrochloride, acetic acid, sodium acetate, and sucrose. People should note that there is a difference between sulfa and sulfite despite their similar names. The FDA Just Authorized Johnson & Johnsons Single-Shot Vaccine for Emergency UseHeres How it Stacks Up, CDC strengthens recommendations and expands eligibility for COVID-19 booster shots, Coronavirus (COVID-19) update: fda takes multiple actions to expand use of pfizer-biontech covid-19 vaccin, Coronavirus (COVID-19) update: FDA expands eligibility for Pfizer-BioNTech covid-19 vaccine booster dose to children 5 through 11 years, Pfizer-BioNTech COVID-19 vaccine fact sheet for healthcare providers administering caccine (Vaccine providers), Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection, Lipids (including ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 2 [(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, 1,2-Distearoyl-sn-glycero-3- phosphocholine, and cholesterol). A day later, she had recovered and was discharged. Toll-free: 1-888-771-7747, Allergic Living The same data have been equally reassuring when it comes to infants born to vaccinated individuals. Scientists created the vaccine mRNA in a laboratory to encode a portion of the spike protein found on the surface of SARS-CoV-2, the virus that causes COVID-19. As PEG is a component of the mRNA vaccines, is that safe for people with soy allergy? Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. health information, we will treat all of that information as protected health MPL is a purified fat-like substance. Coronavirus (COVID-19) update: fda takes multiple actions to expand use of pfizer-biontech covid-19 vaccine. That's why the team of allergists says people with a history of food . In a report released Jan. 6, the CDC says it only has confirmed 21 cases of severe allergic reaction out of the first 1.9 million coronavirus vaccine doses administered. While sulfites occur naturally in foodstuffs, sulfa medications do not. Allergy to drugs doesnt mean you are allergic to vaccines.. The Janssen COVID-19 Vaccine includes the following ingredients: recombinant, replication-incompetent adenovirus type 26 expressing the SARS-CoV-2 spike protein, citric acid monohydrate, trisodium citrate dihydrate, ethanol, 2-hydroxypropyl--cyclodextrin (HBCD), polysorbate-80, sodium chloride." 4 AS01B is made of up MPL, a purified fat-like substance, and QS-21 which is purified from the bark of the Quillaja saponaria (soap bark) evergreen tree native to central Chile. However, he did say that you should tell your provider if you have this allergy or any other, as "all the providers that are giving the vaccine right now are prepared to deal with allergic reactions, and you should tell them, so that they might take a little bit more precaution.". The latest daily figures for the UK, published on Wednesday, showed a further 533 people have now died within 28. The Mass General study says there are many formulations of PEG, and the component used in the mRNA vaccines is different from the PEG used most commonly in other health-care products.. As we discuss in a separate news report here, the majority of those few cases involved women and those with allergy histories. Two UK healthcare reportedly went into anaphylactic shock after having the jab on the first day of the mass vaccination program on Tuesday - but like some 200,000 US citizens, both of them had a history of allergies. An mRNA molecule codes (or makes instructions) for the protein your body produces. Anyone who has a sulfa allergy should make sure they tell their doctor and pharmacist. With Moderna, the CDC study authors said there were 19 confirmed reports of anaphylaxis, or 2.5 cases for every 1 million people. For instance, there no bovine ingredients similar to those implicated in the past in a small number of reactions to other vaccines. They additionally make this observation: Given that both dairy allergy and alpha-gal are not rare diagnoses, and patients with these conditions were notexcluded from the largetrialsnor the current vaccination program, we would have expectedany dairy/beefassociation tohave arisen by nowif it were the culprit allergen. In keeping with the CDC, they say: Our current recommendationis that patients witha history ofanaphylaxis, which would include patients with severe dairy allergy and alpha-gal allergy, require 30 minutes of observation after getting an mRNA shot. And lastly say Wolfson and Patil, we do not see an official constituent or chemical or stabilizer with cross-reactivityin vaccine ingredients to suggest thatpatients with specific food allergies need caution.. The CDCsays it is safe for those with a history of severe allergies to foods or drugs to get the Pfizer and Moderna vaccines. Certain antibiotics may be used in some vaccine production to help prevent bacterial contamination during manufacturing. For example, antibiotics are used in some production methods for making inactivated influenza virus vaccines. The Moderna COVID-19 Vaccineis a preservative-free frozen suspension for muscle injection. However, Baker notes: PEGderivatives that cause allergies usually involve some different protein. (In other words, you might still qualify for the shot to protect against COVID-19.). In Canada, authorities authorized the Pfizer shot on Dec. 9, 2020, and later gave emergency approval to the Moderna vaccine as well. These substances may be added as stabilizers. False. Book: Mayo Clinic Family Health Book, 5th Edition, Newsletter: Mayo Clinic Health Letter Digital Edition. Keep reading for more on these groups, and for other vaccine news, If You've Done This Recently, You Could Have a Bad Vaccine Reaction. Little by. P.O. Centers for Disease Control and Prevention (CDC). A fact sheet on the FDAs website here discloses the ingredients in the vaccine. Phone: 416-604-0110 When you receive the vaccine, your body makes the protein that resembles the viral protein. If the test is positive, that person would not be a candidate for either of the mRNA vaccines. If you have allergies, make them known to your health-care provider giving the shot. COVID-19 Vaccination. Therefore, these vaccines are totally safe for egg-allergic individuals.. A person will not have to avoid food and drink containing sulfites just because they are sensitive or allergic to sulfa drugs. The body continuously processes formaldehyde, both from what it makes on its own and from what it has been exposed to in the environment. These cells need a source of nutrition, which in some instances may be provided by fetal bovine serum. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Because of that, "lipids are unique to this type of vaccine",Jamie Alan, PhD, an associate professor of pharmacology and toxicology at Michigan State University in East Lansing, Mich., toldHealth. Nancy Messonnier, former director of CDCs National Center for Immunization and Respiratory Diseases, called anaphylaxis to either of the two mRNA vaccines exceedingly rare. The CDC stresses that these are safe vaccines and that, when weighing benefits and risks, the COVID-19 virus remains the far greater health risk. Here's Who Should (and Shouldn't) Get It. The Pfizer shot had 95% efficacy in its study, while the Moderna vaccine had an efficacy rate of 94.1%. Most received epinephrine. The FDA explains on its website here that aluminum salts are added to some vaccines as an adjuvant (a facilitator or supplement), used to enhance the immune response. Accessed Oct. 22, 2019. There is no confirmation that PEG has triggered any of the mRNA vaccine reactions so far. Qualifications: The CDC qualifies the last 2 points to say that people who fit those definitions should not receive mRNA COVID-19 vaccination unless they have been evaluated by an allergist-immunologist and it is determined that the person can safely receive the vaccine (e.g. Most importantly, out of more than 14 million administered COVID-19 vaccines, there have been zero deaths associated with allergic reactions, largely because anaphylaxis is completely treatable with epinephrine injections. Niagara Falls, NY Can poor sleep impact your weight loss goals? 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). It is used in multi-dose vials of some influenza vaccines to prevent the growth of bacteria, as explained by the CDC here and here . Check with your maternal care provider about any vaccine questions you have. However, the vaccine has been proven to be safe for most people. Updated May 17, 2022 The Centers for Disease Control and Prevention reports that more than 220.7 million people across the United States have had two shots of a COVID-19 mRNA vaccine as of May 17, 2022. Prednisone withdrawal: Why taper down slowly? The Pfizer and Moderna shots both contain PEG, which is used to coat and protect each of the mRNA vaccines. Novavax has been safely given to thousands of people around the world. When your body encounters the protein, it creates antibodies. Blumenthal agrees, tellingAllergic Living:Soy allergy is from protein, never plant-derived fatty acids (the lipids that Baker references). A couple of other likely culprits are not allergy-based, but havesymptoms that look much like anaphylaxis. (Read about other potential mRNA vaccine reaction causeshere. Both of. The CDC specifies that the two vaccines do not contain eggs. The amount of formaldehyde in a persons body depends on their weight; babies have lower amounts than adults. But severe reactions . In the first week and a half of the US Covid-19 vaccine effort, the CDC said there have been 21 additional confirmed cases of severe allergic reactions known as anaphylaxis, bringing the.

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